Berengoltz-Zlochin S N, Westerhof P W, Mali W P, Rienks R, Smits P C, Verdaasdonk R M, van der Tweel I, Robles de Medina E O, Borst C
Department of Cardiology, Heart Lung Institute, University Hospital, Utrecht, The Netherlands.
Radiology. 1992 Feb;182(2):409-14. doi: 10.1148/radiology.182.2.1732958.
Percutaneous recanalization of femoropopliteal artery occlusions (1-21 cm; median, 8 cm) was attempted in 50 patients. A 2.2-mm-diameter contact probe catheter connected to a continuous-wave neodymium yttrium aluminum garnet (Nd:YAG) laser was used. The laser was activated (15 W, 1-second pulses) only if too much resistance was met. Balloon angioplasty was performed after successful traversal of the occlusion. Primary success was achieved in 40 of 50 patients (80%). In 20 cases, recanalization was achieved mechanically (cold group). In the other 20 cases, recanalization was achieved with the help of laser irradiation (hot group: 15-405 J; median, 90 J). Except for the length of the obstruction (longer in the cold group), the two groups did not differ in baseline characteristics. Neither the length of the occlusion nor the duration of symptoms correlated with failure or success or with the delivered laser energy. Cold and hot groups did not differ with regard to functional improvement and angiographic patency at 3 and 12 months (94% +/- 4). Thus, brief laser activation doubled the cold primary success rate, but the major action of the laser contact probe is mechanical remodeling of the obstruction.
对50例患者尝试进行股腘动脉闭塞(长度为1 - 21厘米,中位数为8厘米)的经皮再通术。使用连接连续波钕钇铝石榴石(Nd:YAG)激光的直径2.2毫米的接触探头导管。仅在遇到过大阻力时才激活激光(15瓦,1秒脉冲)。成功穿过闭塞段后进行球囊血管成形术。50例患者中有40例(80%)获得了初步成功。20例通过机械方法实现再通(冷组)。另外20例在激光照射帮助下实现再通(热组:15 - 405焦耳;中位数为90焦耳)。除了阻塞长度(冷组更长)外,两组的基线特征无差异。闭塞长度和症状持续时间均与失败或成功以及所输送的激光能量无关。冷组和热组在3个月和12个月时的功能改善和血管造影通畅率方面无差异(94%±4)。因此,短暂的激光激活使冷组的初步成功率翻倍,但激光接触探头的主要作用是对阻塞进行机械重塑。