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染料激光辅助多纤维导管血管成形术:29例周围动脉闭塞症治疗的短期结果

Dye laser-assisted angioplasty with multifiber catheters: short-term results in the treatment of 29 peripheral arterial occlusions.

作者信息

Huppert P E, Duda S H, Seboldt H, Claussen C D

机构信息

Department of Diagnostic Radiology, Eberhard-Karls-University Tübingen, Germany.

出版信息

AJR Am J Roentgenol. 1991 Dec;157(6):1253-7. doi: 10.2214/ajr.157.6.1950876.

Abstract

The use of pulsed dye laser energy for angioplasty offers the possibility of ablating atherosclerotic plaques without thermal damage to the adjacent arterial wall. However, to be of value, systems that deliver the energy safely and effectively are required. We tested multifiber catheters in 504-nm pulsed dye laser angioplasty for treatment of peripheral arterial occlusions. Flexible multifiber catheters consist of 12 (7-French) and 19 (9-French) concentrically arranged 200-microns quartz fibers allowing guidewire-directed use. Laser-assisted angioplasty was performed in 2- to 13-cm- (mean, 7.5-cm) long occlusions of iliac (six) and femoropopliteal (23) arteries in patients with symptomatic occlusive vascular disease. Angiograms were obtained before and after laser ablation, after subsequent balloon dilatation, and if signs or symptoms indicated restenosis, during follow-up. The laser procedure was impossible to perform in three (10%) of 29 patients; this was related to unsuccessful passage of the wire in one patient and to inability to advance the laser catheter across the lesion in two patients. In one other patient, reocclusion occurred 1 day after angioplasty. Stand-alone laser angioplasty relieved residual stenosis of less than 30% in six (26%) of 23 femoropopliteal arteries, making balloon dilatation dispensable. Immediate clinical improvement was achieved in 26 (90%) of 29 patients. Laser treatment caused no perforation and no embolization, but minor dissections occurred in 36% of the patients. Our experience suggests that pulsed dye laser angioplasty via multifiber catheters converts arterial occlusions into stenoses. With the exception of angioplasty in distal femoropopliteal arteries, additional balloon dilatation is necessary to complete recanalization.

摘要

使用脉冲染料激光能量进行血管成形术为消融动脉粥样硬化斑块提供了可能性,且不会对相邻动脉壁造成热损伤。然而,要使其具有价值,则需要能够安全有效地输送能量的系统。我们对用于504纳米脉冲染料激光血管成形术的多光纤导管进行了测试,以治疗外周动脉闭塞。柔性多光纤导管由12根(7法式)和19根(9法式)同心排列的200微米石英纤维组成,允许在导丝引导下使用。对有症状的闭塞性血管疾病患者的髂动脉(6例)和股腘动脉(23例)进行2至13厘米(平均7.5厘米)长的闭塞病变的激光辅助血管成形术。在激光消融前后、随后的球囊扩张后以及如果有体征或症状提示再狭窄,则在随访期间进行血管造影。在29例患者中有3例(10%)无法进行激光手术;这与1例患者导丝通过不成功以及2例患者无法将激光导管推进穿过病变有关。在另一例患者中,血管成形术后1天发生再闭塞。单纯激光血管成形术使23例股腘动脉中的6例(26%)残余狭窄减轻至30%以下,使得球囊扩张不再必要。29例患者中有26例(90%)立即获得临床改善。激光治疗未导致穿孔和栓塞,但36%的患者发生了轻微夹层。我们的经验表明,通过多光纤导管进行脉冲染料激光血管成形术可将动脉闭塞转变为狭窄。除了在股腘动脉远端进行血管成形术外,还需要额外的球囊扩张来完成再通。

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