[Bcl-2 expression following the brain concussion in rats].

OBJECTIVE

To evaluate the expression of Bcl-2 protein after brain concussion.

METHODS

Expression levels of Bel-2 protein in cortex, pontine and cerebellum of rats were investigated using immunohistochemistry.

RESULTS

There was no expression of Bcl-2 protein in control group seen. The expression of Bcl-2 protein in brain concussion groups was detected at l hour, and the expression level reached its peak 4 days after the concussion and then declined gradually.

CONCLUSION

Our findings suggest that the detection of Bel-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.