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[卡特——挪威一种新的滥用药物]

[Khat--a new drug of abuse in Norway].

作者信息

Al-Samarraie Muhammad, Khiabani Hassan Z, Opdal Mimi Stokke

机构信息

Divisjon for rettstoksikologi og rusmiddelforskning Nasjonalt folkehelseinstitutt Postboks 4404 Nydalen 0403 Oslo.

出版信息

Tidsskr Nor Laegeforen. 2007 Mar 1;127(5):574-6.

PMID:17332809
Abstract

BACKGROUND

The stimulating drug, Khat, is a drug of abuse that has become known in Norway due to increased immigration from East-Africa, especially Somalia.

METHOD

Review of recent literature.

RESULTS

Khat is present in leaves from the tree Catha Edulis and is taken by chewing the leaves. The biologically active compounds are cathinone, cathine and norephedrine. Analysis of cathinone in urine can be performed at the Norwegian Institute of Public Health. The effects of khat are similar to, but weaker than those of amphetamine. Khat stimulates the central nervous system causing increased alertness, euphoria and occasionally psychosis, and increases activity in the peripheral sympathetic nervous system leading to palpitations, increased blood pressure, large pupils and red eyes. Tannin in khat damages teeth and causes constipation. With increased use of khat in the society it is important for the clinician to have some knowledge of the effects of khat.

摘要

背景

刺激性药物巧茶是一种滥用药物,由于来自东非尤其是索马里的移民增加,在挪威为人所知。

方法

回顾近期文献。

结果

巧茶存在于巧茶属植物的叶子中,通过咀嚼叶子来摄入。生物活性化合物是卡西酮、去甲伪麻黄碱和去甲麻黄碱。挪威公共卫生研究所可对尿液中的卡西酮进行分析。巧茶的作用与安非他明相似,但较弱。巧茶刺激中枢神经系统,导致警觉性提高、欣快感,偶尔还会引发精神病,并增加外周交感神经系统的活动,导致心悸、血压升高、瞳孔放大和眼睛发红。巧茶中的单宁会损害牙齿并导致便秘。随着社会上巧茶使用的增加,临床医生了解巧茶的作用很重要。

相似文献

1
[Khat--a new drug of abuse in Norway].[卡特——挪威一种新的滥用药物]
Tidsskr Nor Laegeforen. 2007 Mar 1;127(5):574-6.
2
[Khat-induced psychosis?].[卡塔叶所致精神病?]
Tijdschr Psychiatr. 2007;49(10):763-7.
3
Khat induced psychosis and its medico-legal implication: a case report.巧茶所致精神障碍及其法医学意义:一例报告
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Khat: pharmacological and medical aspects and its social use in Yemen.巧茶:药理学、医学方面及其在也门的社会用途
Phytother Res. 2002 Aug;16(5):403-13. doi: 10.1002/ptr.1106.
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Khat (Catha edulis): health aspects of khat chewing.巧茶(恰特草):嚼食巧茶对健康的影响
East Mediterr Health J. 2007 May-Jun;13(3):706-18.
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Khat habit and its health effect. A natural amphetamine.巧茶成瘾及其对健康的影响。一种天然安非他命。
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2004 Jul;148(1):11-5.
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A review of the neuropharmacological properties of khat.巧茶的神经药理学特性综述。
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1147-66. doi: 10.1016/j.pnpbp.2007.12.033. Epub 2008 Jan 17.
8
Risk assessment of khat use in the Netherlands: a review based on adverse health effects, prevalence, criminal involvement and public order.荷兰恰特草使用的风险评估:基于健康不良影响、流行率、犯罪关联及公共秩序的综述
Regul Toxicol Pharmacol. 2008 Dec;52(3):199-207. doi: 10.1016/j.yrtph.2008.08.005. Epub 2008 Aug 22.
9
[Khat: from traditional usage to risk of drug addiction].[卡塔叶:从传统用途到药物成瘾风险]
Med Trop (Mars). 1994;54(2):141-4.
10
Khat (Catha edulis)-an updated review.巧茶(恰特草,Catha edulis)——最新综述。
Addict Biol. 2005 Dec;10(4):299-307. doi: 10.1080/13556210500353020.

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World J Psychiatry. 2022 Oct 19;12(10):1268-1286. doi: 10.5498/wjp.v12.i10.1268.
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Toxic effect of khat () on memory: Systematic review and meta-analysis.巧茶对记忆的毒性作用:系统评价与荟萃分析。
J Neurosci Rural Pract. 2017 Jan-Mar;8(1):30-37. doi: 10.4103/0976-3147.193524.
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Qat Chewing and Risk of Potentially Malignant and Malignant Oral Disorders: A Systematic Review.
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Khat chewing and health related quality of life: cross-sectional study in Jazan region, Kingdom of Saudi Arabia.阿拉伯沙特王国吉赞地区咀嚼恰特草与健康相关生活质量的横断面研究。
Health Qual Life Outcomes. 2014 Apr 4;12:44. doi: 10.1186/1477-7525-12-44.
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Chronic khat () and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats.长期咀嚼巧茶()和饮酒对雄性大鼠的全血细胞计数、临床化学指标及睾酮水平有轻微影响。
J Exp Pharmacol. 2013 Jun 24;2013(5):33-44. doi: 10.2147/JEP.S46635.
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Why would khat chewers quit? An in-depth, qualitative study on Saudi Khat quitters.为什么卡特咀嚼者会放弃?一项关于沙特卡特放弃者的深入定性研究。
Subst Abus. 2013;34(4):389-95. doi: 10.1080/08897077.2013.783526.