Toxic effect of khat () on memory: Systematic review and meta-analysis.

BACKGROUND

People use khat () for its pleasant stimulant effect of physical activity, consciousness, motor, and mental functions. Although there are reports assessing the effect of khat on memory, there was no study based on formal systematic review and meta-analysis.

OBJECTIVE

We have therefore conducted this meta-analysis to determine the level of evidence for the effect of khat ( Forsk) on memory discrepancy.

METHODS

MEDLINE, Cochrane Library, PubMed, Academic Search Complete, SPORTDiscus, ScienceDirect, Scopus, Web of Science, and Google Scholar were searched to retrieve the papers for this review. Keywords utilized across database search were khat, cat, chat, long-term memory, short-term memory, memory deficit, randomized control trial, and cross-sectional survey. The search was limited to studies in humans and rodents; published in English language.

RESULT

Finding of various studies included in our meta-analysis showed that the effect of acute, and subchronic exposure to khat showed that short-term memory appears to be affected depending on the duration of exposure. However, does not have any effect on long-term memory.

CONCLUSION

Although a number of studies regarding the current topic are limited, the evidenced showed that khat () induced memory discrepancy.