Mansour A A, Al-Rbeay T B
Department of Medicine, Basra College of Medicine, Iraq.
East Mediterr Health J. 2006 Sep;12(5):504-8.
To determine the effect of adjunct therapy, we carried out a prospective cohort study on 190 patients with tuberculous pleural effusion during May 2003-April 2004. Patients were divided into 3 groups. All groups were treated with anti-tuberculosis (TB) drugs for 6 months; in group 2 (n = 46) prednisolone, 30 mg/day for 10 days, was added; group 3 (n = 78) were given paracentesis to remove fluid. Fever and constitutional symptoms disappeared faster in group 2 (P > 0.05). After 10 days, there was a significantly greater reduction in the size of pleural effusion in group 2, but after 6 months the difference was not statistically significant. We found corticosteroids and therapeutic paracentesis are not necessary in the management of TB pleural effusion.
为确定辅助治疗的效果，我们于2003年5月至2004年4月对190例结核性胸腔积液患者进行了一项前瞻性队列研究。患者被分为3组。所有组均接受抗结核药物治疗6个月；第2组（n = 46）加用泼尼松龙，30 mg/天，共10天；第3组（n = 78）进行胸腔穿刺抽液。第2组发热和全身症状消失更快（P > 0.05）。10天后，第2组胸腔积液大小的减少更为显著，但6个月后差异无统计学意义。我们发现皮质类固醇和治疗性胸腔穿刺在结核性胸腔积液的管理中并非必要。
