Lishner M, Zemlickis D, Degendorfer P, Panzarella T, Sutcliffe S B, Koren G
Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.
Br J Cancer. 1992 Jan;65(1):114-7. doi: 10.1038/bjc.1992.21.
The peak incidence of Hodgkin's disease occurs during the reproductive age, and its association with pregnancy is at a rate of between 1:1,000-1:6,000. We studied the effects of Hodgkin's Disease on the course and survival of 48 women who had Hodgkin's Disease and who were pregnant, and compared their outcome with non-pregnant matched women who were of similar stage of disease, age at diagnosis, and calenderic year of treatment. Twenty-year survival of pregnant women with Hodgkin's Disease was not different from that of their matched controls. Pregnant women with Hodgkin's Disease had similar distribution of stages to the controls.
霍奇金淋巴瘤的发病高峰出现在生育年龄,其与妊娠的关联发生率在1:1000至1:6000之间。我们研究了霍奇金淋巴瘤对48例患有霍奇金淋巴瘤且处于妊娠期女性病程和生存情况的影响,并将她们的结局与疾病分期、诊断时年龄及治疗年份相匹配的非妊娠女性进行比较。患有霍奇金淋巴瘤的妊娠女性20年生存率与匹配的对照组无差异。患有霍奇金淋巴瘤的妊娠女性与对照组的分期分布相似。