Akgül Turgay, Nuhoğlu Bariş, Ayyildiz Ali, Balci Uğur, Ayyildiz Sema Nur, Germiyanoğlu Cankon
Second Urology Clinic, Ministry of Health Ankara Training and Research Hospital, Ankara, Turkey.
Int Urol Nephrol. 2007;39(4):1001-4. doi: 10.1007/s11255-006-9169-3. Epub 2007 Mar 3.
To investigate carbohydrate antigen (CA 19-9, CA 15-3, and CA 125) levels in the patients who had hydronephrosis with renal stones and in whom Extracorporeal shock wave lithotripsy (ESWL) was performed.
This prospective study included 20 people with no known disease for control group and 30 patients who had hydronephrosis with renal stones and in whom ESWL was performed between January 2005 and January 2006. None of patients had urinary infection and malignancy. The blood for carbohydrate antigens was taken pre-ESWL and 30 min after ESWL in both groups. CA 19-9, CA 15-3, and CA 125 in the serum were tested with the electro-immunoassay method on the Roche E-170 apparatus with the original Roche kit.
The CA 19-9 and CA 125 values in the patients group were found to be statistically significant when compared with the control group but the CA 15-3 was not found to be significant. However, CA 19-9, CA 15-3, and CA 125 values of post-ESWL were not statistically significant when compared with pre-ESWL group (P > 0.05).
The average serum values of CA 125 and CA 19-9 in patients were found to be significantly high. However, serum values of CA 19-9, CA 15-3, and CA 125 were not affected by ESWL.
研究肾结石伴肾积水且接受体外冲击波碎石术（ESWL）的患者体内糖类抗原（CA 19-9、CA 15-3和CA 125）水平。
这项前瞻性研究纳入了20名无已知疾病的人作为对照组，以及30名在2005年1月至2006年1月期间患有肾结石伴肾积水且接受了ESWL的患者。所有患者均无泌尿系统感染和恶性肿瘤。两组患者均在ESWL术前及术后30分钟采集糖类抗原检测血样。血清中的CA 19-9、CA 15-3和CA 125采用罗氏原装试剂盒，在罗氏E-170仪器上用免疫比浊法进行检测。
与对照组相比，患者组的CA 19-9和CA 125值具有统计学意义，但CA 15-3值无统计学意义。然而，与ESWL术前组相比，ESWL术后的CA 19-9、CA 15-3和CA 125值无统计学意义（P>0.05）。
发现患者的CA 125和CA 19-9平均血清值显著升高。然而，ESWL未影响CA 19-9、CA 15-3和CA 125的血清值。
