[马德里社区托斯卡纳病毒的年龄依赖性血清流行率：1993 - 1994年和1999 - 2000年]
[Age-dependent seroprevalence of Toscana virus in the Community of Madrid: 1993-1994 and 1999-2000].
作者信息
de Ory-Manchón Fernando, Sanz-Moreno Juan Carlos, Aranguez-Ruiz Emiliano, Ramírez-Fernández Rosa
机构信息
Servicio de Microbiología Diagnóstica, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, España.
出版信息
Enferm Infecc Microbiol Clin. 2007 Mar;25(3):187-9. doi: 10.1157/13099371.
OBJECTIVE
The aim of this study was to assess the seroprevalence of Toscana virus (TOSV) in the Community of Madrid.
METHODS
Samples from two serosurveys obtained during 1993-1994 (2262 individuals) and 1999-2000 (1945 individuals) were studied. Samples were tested by ELISA for TOSV IgG detection.
RESULTS
The seroprevalence of TOSV IgG was significantly higher in 1993-1994 (7.2%; 95% CI 6.2-8.4) than in 1999-2000 (5.7%; 95% CI 4.7-6.9) (chi-square, p < 0.05). In both periods, the prevalence increased significantly with age.
CONCLUSION
These results confirm that TOSV has been circulating in the Community of Madrid over the last years.
目的
本研究旨在评估马德里自治区托斯卡纳病毒（TOSV）的血清阳性率。
方法
对1993 - 1994年（2262人）和1999 - 2000年（1945人）两次血清学调查采集的样本进行研究。通过酶联免疫吸附测定法（ELISA）检测样本中的TOSV IgG。
结果
1993 - 1994年TOSV IgG的血清阳性率（7.2%；95%可信区间6.2 - 8.4）显著高于1999 - 2000年（5.7%；95%可信区间4.7 - 6.9）（卡方检验，p < 0.05）。在两个时期，患病率均随年龄显著增加。
结论
这些结果证实，过去几年TOSV一直在马德里自治区传播。
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