Maffeis Claudio, Castellani Marta
Department of Mother and Child, Biology-Genetics, Pediatrics Section, University of Verona, Verona, Italy.
Nutr Metab Cardiovasc Dis. 2007 Jun;17(5):394-408. doi: 10.1016/j.numecd.2006.08.006. Epub 2007 Mar 2.
Physical activity is the only component of total energy expenditure that can be voluntarily modified. Therefore, it is a reasonable behavioral target for the prevention and treatment of obesity. Most of the fat oxidized daily in the body occurs in skeletal muscle. Physical activity increases the amount of oxidized fat, which helps control fat mass. Moreover, skeletal muscle is an efficient blood glucose utilizer, and regular physical activity promotes insulin sensitivity and glucose homeostasis independently of its effect on body fat. The primary purpose of this study was to provide further insight into the metabolic effects of physical activity, especially on the regulation of energy expenditure, substrate oxidation and body composition. Also of interest is the analysis of available evidence that justifies the recommendation of physical activity programs in the treatment of childhood obesity.
身体活动是总能量消耗中唯一可以自主调节的组成部分。因此，它是预防和治疗肥胖症的合理行为目标。人体每天氧化的大部分脂肪都发生在骨骼肌中。身体活动会增加氧化脂肪的量，这有助于控制脂肪量。此外，骨骼肌是一种高效利用血糖的组织，规律的身体活动可促进胰岛素敏感性和葡萄糖稳态，而与它对身体脂肪的影响无关。本研究的主要目的是进一步深入了解身体活动的代谢效应，尤其是对能量消耗、底物氧化和身体成分调节的影响。同样值得关注的是，分析现有证据，这些证据为在儿童肥胖症治疗中推荐身体活动计划提供了依据。
