Frequency of cytokine gene promoter polymorphisms in the Northern Ireland cystic fibrosis population.
作者信息
Watt Alison P, Ross Owen A, Courtney Julia, Middleton Derek, Ennis Madeleine, Elborn J Stuart
机构信息
Respiratory Research Group, The Queen's University of Belfast, United Kingdom.
出版信息
J Cyst Fibros. 2007 Sep;6(5):363-5. doi: 10.1016/j.jcf.2007.01.002. Epub 2007 Mar 1.
PMID:17336597
Abstract
It has been postulated that cytokine allele frequencies are gender and perhaps geographically-specific. Cytokine release is crucial in the regulation of the type and magnitude of the immune response. This study observed no differences in the frequency of cytokine promoter polymorphisms associated with variant levels of expression in patients with CF and a non-CF population of Northern Ireland.
摘要
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