Stomeo Francesco, Padovani Davide, Bozzo Corrado, Pastore Antonio
ENT Department, University of Ferrara, St. Anna Hospital, Corso Giovecca 203, Ferrara, Italy.
Auris Nasus Larynx. 2007 Sep;34(3):405-8. doi: 10.1016/j.anl.2007.01.001. Epub 2007 Mar 6.
Solitary fibrous tumours (SFT) are rare neoplasms, with an uncommon laryngeal involvement. Only five cases of laryngeal localization have been described in literature. The following is a case of a 75-year-old man with a supraglottic neoplasm of the larynx; after the biopsy immunohistochemical study demonstrated a strong positivity for vimentin, CD34 and Bcl-2. The neoplasm was consequently classified as a SFT. CO(2) laser surgery of the supraglottic larynx, with a wide excision of the neoplasm, was performed. Twenty-four months on, the patient is alive, well and free of disease. Surgical resection is the treatment of choice for laryngeal SFT, but tumour-free resection margins must be achieved to prevent the possibility of local recurrence. Endoscopic resection by means of the CO(2) laser must be accurately planned with MRI or CT imaging to confirm of this kind of surgery.
孤立性纤维瘤（SFT）是一种罕见的肿瘤，累及喉部的情况并不常见。文献中仅描述了5例喉部定位的病例。以下是一名75岁男性患有声门上喉部肿瘤的病例；活检后免疫组织化学研究显示波形蛋白、CD34和Bcl-2呈强阳性。因此，该肿瘤被归类为SFT。对声门上喉部进行了CO2激光手术，并广泛切除了肿瘤。24个月后，患者存活良好，无疾病。手术切除是喉部SFT的首选治疗方法，但必须获得无肿瘤的手术切缘以防止局部复发的可能性。必须通过MRI或CT成像准确规划CO2激光内镜切除术，以确认这种手术的可行性。
