Hocevar Alojzija, Rainer Sasa, Rozman Blaz, Zor Polonca, Tomsic Matija
Department of Rheumatology, University Medical Centre, Vodnikova 62, 1000 Ljubljana, Slovenia.
Eur J Radiol. 2007 Sep;63(3):379-83. doi: 10.1016/j.ejrad.2007.02.003. Epub 2007 Mar 6.
The aim of our study was to determine the reproducibility of a new semi-quantitative scoring system based on ultrasonographic (US) evaluation of structural changes of salivary glands in primary Sjögren's syndrome (SS). US evaluation of parotid and submandibular glands was performed in 28 SS patients and 29 control subjects independently by two blinded observers. Echogenicity, delineation of glandular borders and sonographic structure (homogeneity, hypoechoic areas, hyperechoic foci) of salivary glands were semi-quantitatively assessed and the final US score calculated. Inter-observer variability was determined by Cohen's test. A high degree of inter-observer agreement was found regarding the final US score (0.90) and in the assessment of glandular homogeneity (0.90), echogenicity (0.88) and hypoechoic areas (0.88). This study showed good reproducibility of the US evaluation of salivary glands using our novel scoring system. This may have important implications on the diagnostic algorithm in patients with SS.
我们研究的目的是确定一种基于超声（US）评估原发性干燥综合征（SS）唾液腺结构变化的新半定量评分系统的可重复性。两名盲法观察者独立对28例SS患者和29例对照者的腮腺和颌下腺进行US评估。对唾液腺的回声性、腺边界的清晰度以及超声结构（均匀性、低回声区、高回声灶）进行半定量评估，并计算最终的US评分。观察者间的变异性通过科恩检验确定。在最终US评分（0.90）以及腺均匀性（0.90）、回声性（0.88）和低回声区（0.88）的评估方面，观察者间具有高度一致性。本研究表明，使用我们新的评分系统对唾液腺进行US评估具有良好的可重复性。这可能对SS患者的诊断算法具有重要意义。
