[环核苷酸对淋巴细胞转化和增殖的影响]
[Effect of cyclic nucleotides on the transformation and proliferation of lymphocytes].
作者信息
Di Padova F
出版信息
Boll Ist Sieroter Milan. 1975 Nov 20;54(5):387-92.
PMID:173378
Abstract
When the studies on the immunologic system have met with the "second messenger" hypothesis of the cyclic nucleotides, new ideas have arisen about mechanisms regulating the immunologic reactions. Several works sustain a specific action of cyclic AMP and cyclic GMP to modulate the immunologic system, but the more subtle actions must be discovered. A hypothesis which attributes the control-task of the cellular functions to the c-AMP/c-GMP relation is presented.
摘要
当免疫系统的研究与环核苷酸的“第二信使”假说相遇时，关于调节免疫反应机制的新观点应运而生。一些研究支持环磷酸腺苷（cAMP）和环磷酸鸟苷（cGMP）对免疫系统进行调节的特定作用，但更微妙的作用仍有待发现。本文提出了一种假说，即将细胞功能的控制任务归因于cAMP/cGMP关系。
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