Sirenko I A, Korpliakova G I, Sirota P I, Marchenko O I
Institute of Advance Training for Doctors, Khar'kov.
Probl Tuberk. 1997(3):4-6.
Infection with tuberculosis was studied in 3509 adolescents aged 15 years from various social groups via twice BCG revaccination by analyzing the responses to Mantoux tests with 2 TU of tuberculin purified protein derivative and by following them up for 3 years with an annual examination of the same group. The rates of infection among the teenagers was found to be 32.1% and higher (58.5%) in persons without vaccination signs, but with the latter they depend upon the time after BCG vaccination: 0.7% 3 years after the second revaccination, 30.2% after the first revaccination, and 66.8% 15 years following the first vaccination. The timely and qualitative antituberculosis immunization during twice revaccination contributes to reduced infection rates among teenagers.
通过对3509名来自不同社会群体的15岁青少年进行两次卡介苗复种,并分析他们对2 TU结核菌素纯蛋白衍生物的结核菌素试验反应,以及对同一组人群进行为期3年的年度检查随访,研究了结核病感染情况。未接种卡介苗迹象的青少年感染率为32.1%,而无接种迹象者感染率更高(58.5%),但对于接种过卡介苗的青少年,感染率取决于卡介苗接种后的时间:第二次复种后3年为0.7%,第一次复种后为30.2%,第一次接种后15年为66.8%。两次复种期间及时且高质量的抗结核免疫有助于降低青少年的感染率。