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创伤后应激障碍:紧跟应激研究前沿

Medical post-traumatic stress disorder: catching up with the cutting edge in stress research.

作者信息

Weinert Craig, Meller William

机构信息

Pulmonary, Allergy and Critical Care Medicine, University of Minnesota Medical School, Minneapolis MN 55455, USA.

出版信息

Crit Care. 2007;11(1):118. doi: 10.1186/cc5697.

Abstract

We briefly summarize two original research papers and a review article. We then review the formal structure of the diagnosis of post-traumatic stress disorder (PTSD) and discuss the use of continuous measures of PTSD in comparison with diagnostic instruments. Problems with distinguishing incident from prevalent PTSD cases lead to questions of whether medical PTSD is a new important problem. By examining current studies, we demonstrate that medical PTSD is lagging in fundamental and interventional research but we discuss how medical PTSD has unique opportunities to develop causal models that could inform the greater field of stress studies. We conclude by advocating that future medical PTSD research efforts should focus on understanding how fundamental brain processes are affected during acute medical stress.

摘要

我们简要总结了两篇原创研究论文和一篇综述文章。然后,我们回顾了创伤后应激障碍(PTSD)诊断的正式结构,并讨论了与诊断工具相比,PTSD连续测量方法的使用情况。区分新发PTSD病例和既往PTSD病例的问题引发了关于医源性PTSD是否是一个新的重要问题的疑问。通过审视当前的研究,我们表明医源性PTSD在基础研究和干预研究方面滞后,但我们讨论了医源性PTSD如何有独特的机会来建立因果模型,这些模型可为更广泛的压力研究领域提供信息。我们最后主张,未来医源性PTSD的研究工作应专注于理解急性医疗压力期间基本脑过程是如何受到影响的。

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