Chuang Chih-Chieh, Lin Hou-Chun, Huang Chia-Wen
Department of Otolaryngology, Taipei City Hospital Yang-Ming Branch, Taipei, Taiwan.
J Formos Med Assoc. 2007 Feb;106(2):165-8. doi: 10.1016/S0929-6646(09)60234-5.
Inflammatory pseudotumors (IPTs) are a clinically and histologically diverse group of lesions characterized by a tumor mass of acute and chronic inflammatory cells with a variable fibrous response. IPTs most commonly involve the lung and orbit, but rarely the sinonasal tract. We report a 68-year-old male with an IPT of the sinonasal tract presenting as nasal obstruction and postnasal dripping for several years. A gray-white soft mass was noted in the right nasal cavity. Computed tomography revealed a solid mass filling the right nasal cavity and maxillary sinus. Caldwell-Luc operation with ethmoidectomy (right) was conducted to resect the mass en bloc. Pathology revealed admixture of plasma cells, lymphocytes and eosinophils, confirming the diagnosis of IPT. The patient remained symptom-free over 4 years of follow-up. Awareness of the clinical presentations, histopathologic features and treatment of choice of this rare disease entity is necessary to distinguish it from malignancy and avoid unnecessary management.
炎性假瘤（IPTs）是一组临床和组织学表现多样的病变，其特征为肿瘤性肿块，由急性和慢性炎症细胞组成，并伴有不同程度的纤维反应。IPTs最常累及肺部和眼眶，但很少累及鼻窦。我们报告一例68岁男性鼻窦炎性假瘤，表现为鼻塞和鼻后滴漏数年。在右侧鼻腔发现一个灰白色软肿块。计算机断层扫描显示一个实性肿块充满右侧鼻腔和上颌窦。行柯-陆氏手术加（右侧）筛窦切除术，整块切除肿块。病理显示浆细胞、淋巴细胞和嗜酸性粒细胞混合存在，确诊为炎性假瘤。患者随访4年无症状。了解这种罕见疾病实体的临床表现、组织病理学特征和治疗选择，对于将其与恶性肿瘤区分开来并避免不必要的处理是必要的。
