JAK2V617F检测及血清促红细胞生成素定量：血细胞比容升高前来咨询的患者诊断检查的初步步骤。
JAK2V617F detection and dosage of serum erythropoietin: first steps of the diagnostic work-up for patients consulting for elevated hematocrit.
作者信息
Girodon François, Lippert Eric, Mossuz Pascal, Dobo Irène, Boiret-Dupré Nathalie, Lesesve Jean-François, Hermouet Sylvie, Praloran Vincent
出版信息
Haematologica. 2007 Mar;92(3):431-2. doi: 10.3324/haematol.10660.
PMID:17339201
Abstract
The predictive values of common biological criteria for the diagnosis of polycythemia vera were studied in a cohort of patients with high hematocrit. We found JAK2V617F and erythropoietin assays were the most relevant first tests. Classification of patients according to their JAK2V617F status and erythropoietin levels facilitated the choice of further diagnostic investigations.
摘要
在一组高血细胞比容患者中研究了真性红细胞增多症诊断常用生物学标准的预测价值。我们发现JAK2V617F和促红细胞生成素检测是最相关的初步检测。根据患者的JAK2V617F状态和促红细胞生成素水平进行分类有助于选择进一步的诊断检查。
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