May Andreas E, Langer Harald, Seizer Peter, Bigalke Boris, Lindemann Stephan, Gawaz Meinrad
Medizinische Klinik III, Eberhard Karls Universität Tübingen, Tübingen, Germany.
Semin Thromb Hemost. 2007 Mar;33(2):123-7. doi: 10.1055/s-2007-969023.
Inflammatory processes at the vascular wall result in the development of atherosclerosis. Platelet interactions with leukocytes may play a key role in the initiation of inflammation. They trigger autocrine and paracrine activation processes, leading to leukocyte recruitment (in)to the vascular wall. This article highlights the molecular basis and the inflammatory pathways initiated by platelet-leukocyte interactions.
血管壁的炎症过程会导致动脉粥样硬化的发展。血小板与白细胞的相互作用可能在炎症的起始过程中起关键作用。它们触发自分泌和旁分泌激活过程，导致白细胞募集至血管壁。本文重点介绍了血小板 - 白细胞相互作用引发的分子基础和炎症途径。
