Deppe Herbert, Horch Hans-Henning, Neff Andreas
Department of Oral and Maxillofacial Surgery, Technical University of Munich, Germany.
Int J Oral Maxillofac Implants. 2007 Jan-Feb;22(1):79-86.
Recently, histologic studies in the beagle dog model demonstrated that CO2 laser-assisted implant decontamination can result in reosseointegration. Consequently, the purpose of this study was to assess the efficacy of CO2 laser-assisted therapy as compared with conventional therapy, with the concomitant use of beta-tricalcium phosphate, in humans.
The study included 32 patients with 73 ailing implants. In the laser group, 22 implants were treated with soft tissue resection following laser decontamination; whereas in 17 implants, bone augmentation was performed. In the control group, soft tissue resection after conventional decontamination was performed in 19 implants, augmentation in 15 implants. Results were evaluated 4 months after surgery and in May 2004.
Four months after therapy, there were no significant differences in distance from implant shoulder to the first bone contact (ie, DIB values) between implants undergoing laser decontamination and soft tissue resection and implants treated with conventional decontamination followed by soft tissue resection. At the end of the study, there was a statistically significant difference between these 2 groups. Four months after therapy, DIB values after laser decontamination and augmentation were significantly more favorable than after conventional decontamination and augmentation. This difference was no longer detectable at the end of the study.
Based on the results of this study, it may be concluded that the treatment of peri-implantitis may be accelerated by using a CO2 laser concomitant with soft tissue resection. However, with respect to long-term results in augmented defects, there seems to be no difference between laser and conventional decontamination.
最近,在比格犬模型上进行的组织学研究表明,二氧化碳激光辅助种植体去污可导致再骨结合。因此,本研究的目的是评估与传统治疗相比,在人类中同时使用β-磷酸三钙的二氧化碳激光辅助治疗的疗效。
本研究纳入32例患者,共73颗患病种植体。激光组中,22颗种植体在激光去污后进行软组织切除;17颗种植体进行了骨增量。对照组中,19颗种植体在传统去污后进行软组织切除,15颗种植体进行增量。在术后4个月和2004年5月对结果进行评估。
治疗4个月后,接受激光去污和软组织切除的种植体与接受传统去污后再进行软组织切除的种植体相比,从种植体肩部到首次骨接触的距离(即DIB值)无显著差异。在研究结束时,这两组之间存在统计学上的显著差异。治疗4个月后,激光去污和增量后的DIB值明显优于传统去污和增量后的DIB值。在研究结束时,这种差异不再明显。
基于本研究结果,可以得出结论,使用二氧化碳激光并结合软组织切除可能会加速种植体周围炎的治疗。然而,就骨增量缺损的长期结果而言,激光去污和传统去污之间似乎没有差异。