Wojtaszek Ewa, Ostrowski Grzegorz, Niemczyk Stanisław, Lange Jacek, Grzejszczak Agnieszka, Matuszkiewicz-Rowińska Joanna
Katedra i Klinika Nefrologii, Dializoterapii i Chorób Wewnetrznych AM w Warszawie.
Pol Arch Med Wewn. 2006 Jul;116(1):678-82.
Fungal peritonitis is a serious complication causes significant morbidity and mortality for patients on peritoneal dialysis. We reviewed our fungal peritonitis cases to analyse clinical features, treatment and predisposing factors.
Records of all peritonitis episodes were reviewed. Fungal peritonitis was diagnosed based on positive fungal culture in suitable media of the effluent.
Between January 2001 and June 2006, 98 patients were treated with peritoneal dialysis. During this period 102 peritonitis episodes was noticed, four of them (3,9%) was caused by fungi. The most common pathogen was Candida sp. Preceding treatment with broad-spectrum antibiotics was revealed in all cases, three of them due to bacterial peritonitis. One patient died due to sepsis, three was moved to hemodialysis.
Fungal peritonitis is rare, but serious complication it patients treated with peritoneal dialysis. Preceding broad-spectrum antibiotic therapy is the main risk factor for the development of this complication. Early Tenckhoff catheter removal and prophylaxis (antifungal treatment, education, coexisting diseases treatment) may be beneficial for peritoneal dialysis patients with fungal peritonitis.
真菌性腹膜炎是腹膜透析患者的一种严重并发症，可导致显著的发病率和死亡率。我们回顾了我们的真菌性腹膜炎病例，以分析其临床特征、治疗方法和诱发因素。
回顾了所有腹膜炎发作的记录。根据流出液在合适培养基中的真菌培养阳性诊断真菌性腹膜炎。
2001年1月至2006年6月期间，98例患者接受了腹膜透析治疗。在此期间，共发现102次腹膜炎发作，其中4次（3.9%）由真菌引起。最常见的病原体是念珠菌属。所有病例均有广谱抗生素治疗史，其中3例因细菌性腹膜炎接受治疗。1例患者死于败血症，3例转为血液透析。
真菌性腹膜炎虽罕见，但却是腹膜透析患者的严重并发症。先前的广谱抗生素治疗是该并发症发生的主要危险因素。早期拔除Tenckhoff导管并进行预防（抗真菌治疗、教育、治疗并存疾病）可能对患有真菌性腹膜炎的腹膜透析患者有益。
