Montenegro J, Aguirre R, González O, Martinez I, Saracho R
Division of Nephrology, Hospital de Galdakao, Vizcaya, Spain.
Clin Nephrol. 1995 Jul;44(1):60-3.
Candida peritonitis was treated with fluconazole in ten continuous ambulatory peritoneal dialysis (CAPD) patients without immediate removal of the peritoneal catheter. Shortly prior to diagnosis, six patients (60%) had received broad-spectrum antibiotics. Gram stain of peritoneal fluid detected yeast in 70% of cases. In eight patients the peritoneal dialysis catheter was removed within one week of diagnosis because of clinical deterioration. In the majority of cases (90%), candida peritonitis resolved only after catheter removal in spite of ongoing fluconazole therapy. Fluconazole was well tolerated by all patients.
10例持续性非卧床腹膜透析（CAPD）患者发生念珠菌性腹膜炎，采用氟康唑治疗，未立即拔除腹膜导管。在诊断前不久，6例患者（60%）接受了广谱抗生素治疗。70%的病例通过腹膜液革兰氏染色检测到酵母菌。8例患者因临床病情恶化在诊断后1周内拔除了腹膜透析导管。尽管持续使用氟康唑治疗，但在大多数病例（90%）中，念珠菌性腹膜炎仅在拔除导管后才得以缓解。所有患者对氟康唑耐受性良好。
