Lee Andrew W, Davis Cameron, Puttgen H Adrian, Hillis Argye E
Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Phipps 126, Baltimore, MD 21287, USA.
Nat Clin Pract Neurol. 2007 Mar;3(3):173-7. doi: 10.1038/ncpneuro0422.
A 67-year-old right-handed man with a history of atrial fibrillation developed sudden aphasia after urological surgery. Initial diffusion-weighted and perfusion-weighted MRI demonstrated an area of hypoperfusion in Broca's area, with minimal infarction.
Neurological examination, language testing and brain MRI scans with diffusion-weighted and perfusion-weighted imaging.
Acute cardioembolic stroke with minimal infarction in Broca's area and a surrounding region of potentially salvageable, hypoperfused cortex.
Saline-induced hypertension resulting in rapid restoration of cortical perfusion and a resolution of the initial speech and language deficits. The utility of perfusion-weighted imaging in selecting appropriate candidates for urgent treatment of stroke when thrombolysis is contraindicated is discussed.
一名67岁右利手男性，有房颤病史，在泌尿外科手术后突然出现失语。最初的弥散加权成像和灌注加权成像磁共振成像显示布罗卡区有灌注不足区域，梗死灶极小。
神经系统检查、语言测试以及采用弥散加权成像和灌注加权成像的脑部磁共振成像扫描。
急性心源性栓塞性卒中，布罗卡区梗死灶极小，其周围有潜在可挽救的灌注不足皮质区域。
生理盐水诱导高血压使皮质灌注迅速恢复，初始的言语和语言缺陷得以解决。讨论了在溶栓治疗禁忌时，灌注加权成像在选择合适的卒中紧急治疗候选患者中的作用。
