Lin Hsuan-Chih, Chen Mei-Jou, Chou Chen-Han, Young Yi-Ho
Department of Otolaryngology, Lo Tung Poh-Ai Hospital, Ilan, Taiwan.
Auris Nasus Larynx. 2007 Sep;34(3):383-5. doi: 10.1016/j.anl.2007.01.004. Epub 2007 Mar 6.
Although atherothrombotic complications due to ovulation induction are well known in the literature, there is no previous report specifically on the presentation of a lateral medullary infarction. Recently, we have encountered a 36 years old woman with primary infertility having acute vertiginous attack after ovulation induction. Audiovestibular test battery revealed bilateral normal hearing, bilateral gaze nystagmus, rebound nystagmus beating toward the right side, loss of visual suppression with augmentation of caloric nystagmus in light on the left side, and delayed vestibular evoked myogenic potentials on the left side, which was subsequently confirmed as lateral medullary syndrome by MRI scan. In this patient, polycystic ovary syndrome plus high levels of follicle stimulating hormone (FSH) and estrogen, together with S protein deficiency may precipitate the occurrence of lateral medullary infarct after ovulation induction. Thus, in vitro fertilization treatment protocol has been terminated.
虽然文献中已熟知排卵诱导导致的动脉粥样硬化血栓形成并发症，但此前尚无关于外侧延髓梗死表现的具体报道。最近，我们遇到一名36岁的原发性不孕女性，在排卵诱导后出现急性眩晕发作。听-前庭综合检查显示双侧听力正常、双侧凝视性眼球震颤、向右侧跳动的反弹性眼球震颤、左侧光刺激时热刺激诱发的眼球震颤视觉抑制丧失及增强，以及左侧前庭诱发肌源性电位延迟，随后经磁共振成像扫描确诊为外侧延髓综合征。在该患者中，多囊卵巢综合征加上高水平的促卵泡生成素（FSH）和雌激素，再加上S蛋白缺乏，可能促使排卵诱导后外侧延髓梗死的发生。因此，体外受精治疗方案已终止。
