Esmaillzadeh Ahmad, Kimiagar Masoud, Mehrabi Yadollah, Azadbakht Leila, Hu Frank B, Willett Walter C
Department of Nutrition, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Am J Clin Nutr. 2007 Mar;85(3):910-8. doi: 10.1093/ajcn/85.3.910.
Although individual foods and nutrients have been associated with the metabolic syndrome, whether dietary patterns identified by factor analysis are also associated with this syndrome is not known.
We aimed to evaluate the association of major dietary patterns characterized by factor analysis with insulin resistance and the metabolic syndrome among women.
Usual dietary intakes were assessed in a cross-sectional study of 486 Tehrani female teachers aged 40-60 y. Anthropometric and blood pressure measurements were performed, and fasting blood samples were taken for biomarker assessment. The metabolic syndrome was defined according to Adult Treatment Panel III guidelines, and insulin resistance was defined as the highest quartile of the homeostasis model assessment scores.
We identified 3 major dietary patterns by factor analysis: the healthy dietary pattern, the Western dietary pattern, and the traditional dietary pattern. After control for potential confounders, subjects in the highest quintile of healthy dietary pattern scores had a lower odds ratio for the metabolic syndrome (odds ratio: 0.61; 95% CI: 0.30, 0.79; P for trend < 0.01) and insulin resistance (0.51; 0.24, 0.88; P for trend < 0.01) than did those in the lowest quintile. Compared with those in the lowest quintile, women in the highest quintile of Western dietary pattern scores had greater odds for the metabolic syndrome (1.68; 1.10, 1.95; P for trend < 0.01) and insulin resistance (1.26; 1.00, 1.78; P for trend < 0.01). Higher consumption of traditional dietary pattern was significantly associated only with abnormal glucose homeostasis (1.19; 1.04, 1.59; P < 0.05).
Significant associations exist between dietary patterns identified by factor analysis, the metabolic syndrome, and insulin resistance.
尽管某些特定食物和营养素已被证实与代谢综合征有关，但通过因子分析确定的饮食模式是否也与该综合征相关尚不清楚。
我们旨在评估通过因子分析确定的主要饮食模式与女性胰岛素抵抗及代谢综合征之间的关联。
在一项横断面研究中，对486名年龄在40至60岁的德黑兰女教师的日常饮食摄入量进行了评估。测量了她们的人体测量指标和血压，并采集空腹血样进行生物标志物评估。根据成人治疗小组III的指南定义代谢综合征，将胰岛素抵抗定义为稳态模型评估得分的最高四分位数。
通过因子分析，我们确定了3种主要饮食模式：健康饮食模式、西方饮食模式和传统饮食模式。在控制了潜在混杂因素后，健康饮食模式得分最高五分位数的受试者患代谢综合征的比值比更低（比值比：0.61；95%置信区间：0.30，0.79；趋势P值<0.01），患胰岛素抵抗的比值比也更低（0.51；0.24，0.88；趋势P值<0.01），相比最低五分位数的受试者。与最低五分位数的女性相比，西方饮食模式得分最高五分位数的女性患代谢综合征的可能性更大（1.68；1.10，1.95；趋势P值<0.01），患胰岛素抵抗的可能性也更大（1.26；1.00，1.78；趋势P值<0.01）。传统饮食模式的摄入量较高仅与血糖稳态异常显著相关（1.19；1.04，1.59；P<0.05）。
通过因子分析确定的饮食模式、代谢综合征和胰岛素抵抗之间存在显著关联。
Zotero 插件