Hélénon O, Attlan E, Legendre C, Hanna S, Denys A, Souissi M, Kreis H, Moreau J F
Department of Radiology, Hôpital Necker, Paris, France.
Radiographics. 1992 Jan;12(1):21-33. doi: 10.1148/radiographics.12.1.1734477.
In 21 recipients of renal transplants suspected of allograft necrosis, the authors correlated the results of imaging to pathologic and histologic data in order to describe the magnetic resonance (MR) imaging and color Doppler ultrasonographic (US) characteristics of infarction. All patients underwent MR imaging performed with and without gadolinium tetraazacyclododecanetetraacetic acid (DOTA) and color Doppler US. Nonenhanced T1-weighted images showed no obvious changes, whereas nonenhanced T2-weighted images demonstrated a slight increase in signal intensity in areas of ischemic necrosis and low or heterogeneous signal intensity in areas of hemorrhagic necrosis. Gd-DOTA-enhanced MR images showed no contrast material uptake in infarcted areas. Color Doppler US characteristics of infarction included absence of Doppler signal and alteration of the cortical echogenic structure, particularly in cases of ischemic necrosis. Color Doppler US allows measurement of vascular resistance and assessment of intrarenal vasculature and the renal pedicle. Gd-DOTA-enhanced MR imaging is useful in confirming the diagnosis of infarction and provides an accurate evaluation of the extent of the infarct.
在21例疑似同种异体移植肾坏死的肾移植受者中，作者将影像学结果与病理和组织学数据进行关联，以描述梗死的磁共振（MR）成像和彩色多普勒超声（US）特征。所有患者均接受了使用和不使用钆喷替酸葡甲胺（DOTA）的MR成像以及彩色多普勒US检查。未增强的T1加权图像未见明显变化，而未增强的T2加权图像显示缺血性坏死区域信号强度略有增加，出血性坏死区域信号强度低或不均匀。钆喷替酸葡甲胺增强的MR图像显示梗死区域无对比剂摄取。梗死的彩色多普勒US特征包括无多普勒信号以及皮质回声结构改变，尤其是在缺血性坏死的病例中。彩色多普勒US可测量血管阻力并评估肾内血管系统和肾蒂。钆喷替酸葡甲胺增强的MR成像有助于确诊梗死，并能准确评估梗死范围。
