Hanna S, Helenon O, Legendre C, Chiche J F, Di Stefano D, Kreis H, Moreau J F
Department of Uro-Radiology, Hôpital Necker, Paris, France.
Acta Radiol. 1991 Jan;32(1):42-6.
The results of 62 consecutive MR examinations were correlated with the subsequent clinical course and histologic results. Twenty-six cases of rejection showed a marked diminution of cortico-medullary differentiation (CMD). The renal parenchymal vascular pattern and visibility of renal sinus fat were not markedly altered in rejection and there was no difference between normal and rejected allograft shape. The ability of MR imaging to diagnose renal transplant rejection is only based on CMD, which, however, is non-specific. In 2 cases of severe acute rejection, T2 weighted images showed an abnormal signal intensity of the cortex due to renal infarction. Our preliminary results in 8 patients with Gd-DOTA injection showed 2 cases with necrosis seen as areas with absent contrast enhancement. This technique seems to be promising in the detection of perfusion defects.
连续62例磁共振检查结果与随后的临床病程及组织学结果相关。26例排斥反应表现为皮髓质分化（CMD）明显减弱。排斥反应时肾实质血管形态及肾窦脂肪显示未明显改变，正常与排斥的同种异体肾外形无差异。磁共振成像诊断肾移植排斥反应的能力仅基于CMD，但CMD是非特异性的。2例严重急性排斥反应中，T2加权像显示由于肾梗死皮质信号强度异常。我们对8例注射钆双胺的患者的初步结果显示，2例出现坏死，表现为对比剂增强缺失区域。该技术在检测灌注缺损方面似乎很有前景。
