Talukder S I, Haque M A, Huq M H, Alam M O, Roushan A, Noor Z, Nahar K
Department of Pathology, Mymensingh Medical College, Mymensingh, Bangladesh.
Mymensingh Med J. 2007 Jan;16(1):81-4. doi: 10.3329/mmj.v16i1.254.
The objective of this study was to explore the histopathological findings and the rate of removal of ovaries in hysterectomy specimens. This study took into account 328 hysterectomy specimens examined in the Department of Pathology, Mymensingh Medical College and in one private Pathology Laboratory in Mymensingh town from March to August, 2005. Formalin fixed paraffin embedded tissue sections stained with haematoxylin and eosin were examined under light microscope. Patients' age, parts of uterus examined and their histopathological findings were retrieved from laboratory records. The common histopathological findings were: chronic cervicitis (87.80%), leiomyoma (17.07%), uterine prolapse (16.72%), adenomyosis (3.96), non-specific endometritis (3.35%), squamous cell carcinoma of cervix (2.44%), endometrial polyp (2.44%), serous cystadenoma of ovary (2.44%) and endometrial hyperplasia (1.83%). Some of the specimens show more than one lesions in the body of uterus, of which coexistence of adenomyosis and leiomyoma was the most common. Neoplastic lesions in cervix were 4.27%, in body 16.92% and in ovaries 5.06%. Malignant neoplasms were found in cervix 71.43%, in uterine corpus 3.03% and in ovaries 25%. Ovaries of both sides were removed in 48.17% of total cases. Their median age was 45 years, lowest age 23 years and maximum age was 82. The rate of removal of both ovaries was found to be increasing with the increase of age. Only one case was found to be subtotal hysterectomy and others were total hysterectomy. The present study revealed that the most common histopathological cause of hysterectomy is chronic cervicitis. Most common neoplastic cause of hysterectomy is leiomyoma. The rationalities and the possible after effect of hysterectomy in sexual functions and other physiological impairment should be followed up.
本研究的目的是探讨子宫切除标本的组织病理学发现及卵巢切除率。本研究纳入了2005年3月至8月在迈门辛医学院病理科及迈门辛镇一家私立病理实验室检查的328例子宫切除标本。用苏木精和伊红染色的福尔马林固定石蜡包埋组织切片在光学显微镜下检查。从实验室记录中获取患者年龄、检查的子宫部位及其组织病理学发现。常见的组织病理学发现为：慢性宫颈炎（87.80%）、平滑肌瘤（17.07%）、子宫脱垂（16.72%）、子宫腺肌病（3.96%）、非特异性子宫内膜炎（3.35%）、宫颈鳞状细胞癌（2.44%）、子宫内膜息肉（2.44%）、卵巢浆液性囊腺瘤（2.44%）和子宫内膜增生（1.83%）。一些标本在子宫体显示不止一种病变，其中子宫腺肌病和平滑肌瘤并存最为常见。宫颈的肿瘤性病变为4.27%，子宫体为16.92%，卵巢为5.06%。恶性肿瘤在宫颈中占71.43%，在子宫体中占3.03%，在卵巢中占25%。48.17%的总病例双侧卵巢均被切除。她们的中位年龄为45岁，最小年龄为23岁，最大年龄为82岁。发现双侧卵巢切除率随年龄增长而增加。仅发现1例为次全子宫切除术，其他均为全子宫切除术。本研究表明，子宫切除最常见的组织病理学原因是慢性宫颈炎。子宫切除最常见的肿瘤性原因是平滑肌瘤。子宫切除在性功能和其他生理损害方面的合理性及可能的后遗症应予以随访。
