Farr R W
Division of Infectious Diseases, University of Colorado Health Sciences Center, Denver.
South Med J. 1992 Jan;85(1):52-3. doi: 10.1097/00007611-199201000-00017.
A patient receiving long-term corticosteroid therapy for asthma had two episodes of Pneumocystis carinii pneumonia (PCP) 8 years apart. She had no other causes of immunosuppression. Experimental evidence indicates that corticosteroid administration causes a reduction in T lymphocytes mediated by suppression of cytokines. Corticosteroid therapy is a rare but possible independent predisposition to PCP.
一名因哮喘接受长期皮质类固醇治疗的患者，在相隔8年的时间里发生了两起卡氏肺孢子虫肺炎（PCP）。她没有其他免疫抑制原因。实验证据表明，给予皮质类固醇会导致细胞因子介导的T淋巴细胞减少。皮质类固醇治疗是PCP罕见但可能的独立易感因素。
