Targońska-Stepniak Bozena, Majdan Maria, Suszek Dorota, Laskowska Katarzyna
Department of Rheumatology and Connective Tissue Diseases, Medical University of Lublin, Poland.
Pol Merkur Lekarski. 2006 Nov;21(125):480-3.
The paper presents diagnostic problems and therapeutic management in a case of 34 year old woman with antiphospholipid syndrome (APS) connected with overlap syndrome: autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). Life threatening cardiac arrhythmia was the first clinical manifestation of the disease. Pulmonary embolism occurred a few months later, with the presence of antiphospholipid antibodies. The diagnosis of AlH and PBC was made as a result of further research of complex immunological disturbances observed in the patient and after liver biopsy.
本文介绍了一名34岁患有抗磷脂综合征（APS）并伴有重叠综合征（自身免疫性肝炎（AIH）和原发性胆汁性肝硬化（PBC））的女性患者的诊断问题及治疗处理。危及生命的心律失常是该疾病的首个临床表现。几个月后出现了肺栓塞，并检测到抗磷脂抗体。通过对患者观察到的复杂免疫紊乱进行进一步研究以及肝脏活检，最终确诊为AIH和PBC。
