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[前列腺中的催乳素受体]

[Prolactin receptors in the prostate].

作者信息

Wylot Marcin, Laszczyńska Maria, Chorzepa Karolina

机构信息

Department of Histology and Embryology, Pomeranian Medical University of Szczecin, Poland.

出版信息

Pol Merkur Lekarski. 2006 Nov;21(125):492-4.

Abstract

Following article describes available information presenting current knowledge on prolactin receptors expression and prolactin actions in the prostate gland. Prostate is strongly androgen dependent gland, however poseses receptors for other ligands including hypophyseal hormones and growth factors. More over prolactin is also locally produced and secreted acting also in paracrine way on the prostate. Prolactin alone and in cooperation with these hormones and growth factors plays essential role in regulation morphology and function of prostate gland, takes part in embryonic development, secretory function and pathological stages in prostate. Studies carried out in the human and animals in vivo and in vitro revealed presence of prolactin receptors in normal, benign and malignant prostate tissues.

摘要

以下文章介绍了有关催乳素受体表达及催乳素在前列腺中的作用的现有信息,这些信息展示了当前的相关知识。前列腺是高度依赖雄激素的腺体,但它也拥有其他配体的受体,包括垂体激素和生长因子。此外,催乳素也在局部产生和分泌,并以旁分泌方式作用于前列腺。催乳素单独或与这些激素及生长因子协同作用,在调节前列腺的形态和功能方面发挥着重要作用,参与前列腺的胚胎发育、分泌功能及病理阶段。在人和动物体内及体外进行的研究表明,正常、良性及恶性前列腺组织中均存在催乳素受体。

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