Wylegała Edward, Moćko Lucyna, Woyna-Orlewicz Anna, Teper Sławomir, Orzechowska-Wylegała Bogusława
Department of Nursing and Social Medical Issues, Silesian Medical University in Katowice, Poland.
Pol Merkur Lekarski. 2006 Nov;21(125):495-7.
Authors present one of the ocular diabetic complications--diabetic keratoepitheliopathy. The aim of this article is to summarize the knowledge about diabetic keratoepitheliopathy, its causes, manifestations and treatment options. Diabetes mellitus is associated with structural and functional disturbances in eyelids, conjunctiva and cornea. There are also changes in tear film present. Diabetic neuropathy resulting from the biochemical poor control of diabetes is the probable basic cause of the pathology. Mechanisms responsible for these changes are still not well understood. The corneal and conjunctival complications may occur spontaneously. But more often they arise from undue stress of intraocular surgery procedures. The incidence of diabetic keratoepitheliopathy in diabetic patients is high. However, it is rarely diagnosed. Effectiveness of symptomatic treatment with use of common medications is not satisfactory and it needs further investigation.
作者介绍了糖尿病眼部并发症之一——糖尿病性角膜上皮病变。本文旨在总结有关糖尿病性角膜上皮病变的知识,包括其病因、表现及治疗选择。糖尿病与眼睑、结膜和角膜的结构及功能紊乱有关。泪膜也存在变化。糖尿病生化控制不佳导致的糖尿病神经病变可能是该病理的基本病因。导致这些变化的机制仍未完全明确。角膜和结膜并发症可能自发出现。但更常见的是由眼内手术操作的不当压力引发。糖尿病患者中糖尿病性角膜上皮病变的发生率较高。然而,它很少被诊断出来。使用常用药物进行对症治疗的效果并不令人满意,需要进一步研究。