Kasuya H, Takeda S, Shimoyama S, Shikano T, Nomura N, Kanazumi N, Nomoto S, Sugimoto H, Nakao A
Department of Surgery II, Nagoya University School of Medicine, Tsurumai-cho 65, Showa-ku, Nagoya 466-8550, Japan.
Curr Cancer Drug Targets. 2007 Mar;7(2):123-5. doi: 10.2174/156800907780058826.
We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their latest review articles for exclusive publication in this special issue. Moreover, this issue also includes a range of opinion from government drug organizations. Here we simply wish to bring together the newest knowledge and experience in the field of cutting-edge oncolytic virus therapy for researchers and every kind of cancer therapist. The Foreword presents a historical perspective on the development of oncolytic virus together with the encouraging results of recent clinical trials (e.g., H101 has been tested in clinical trial of nearly 250 patients and approved for human use by the Chinese FDA, while PV701 has been tried in over 110 patients, as described in our special issue).
我们非常高兴且自豪能够出版《当代癌症药物靶点》的这一特刊,该特刊专注于溶瘤病毒疗法,涵盖了腺病毒、痘苗病毒、疱疹病毒和新城疫病毒的基础与临床研究。在这些论文中,我们迎来了该领域的世界顶级权威人士,他们慷慨地贡献了最新的综述文章,以供在本特刊独家发表。此外,本期还收录了政府药物组织的一系列观点。在此,我们只是希望为研究人员和各类癌症治疗师汇集前沿溶瘤病毒疗法领域的最新知识和经验。前言呈现了溶瘤病毒发展的历史视角以及近期临床试验的鼓舞人心的结果(例如,H101已在近250名患者的临床试验中进行了测试,并被中国食品药品监督管理局批准用于人体,而PV701已在110多名患者中进行了试验,正如我们特刊中所描述的那样)。