van Gestel Yvette R B M, Pedersen Susanne S, van de Sande Meike, de Jaegere Peter P T, Serruys Patrick W, Erdman Ruud A M, van Domburg Ron T
Department of Cardiology, Thoraxcenter, Ba 559, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.
J Affect Disord. 2007 Nov;103(1-3):197-203. doi: 10.1016/j.jad.2007.01.030. Epub 2007 Mar 7.
We examined whether type-D personality exerts a stable effect on anxiety over time and the clinical relevance of type-D personality as a predictor of anxiety 12 months post-percutaneous coronary intervention (PCI).
Consecutive patients (n=416) with stable or unstable angina pectoris treated with PCI completed the Type-D Scale (DS14) at baseline and the Hospital Anxiety and Depression Scale (HADS) at baseline and 12 months.
At baseline, 26% of the patients were anxious, with 67% of these patients still being anxious 12 months post-PCI (p<0.001). There was no significant change in anxiety between baseline and 12 months (p=0.96) nor was the interaction effect type-D personality by time significant (p=0.41). However, type-D patients experienced significantly higher levels of anxiety than non-type-D patients (p<0.001). Type-D personality (OR: 2.89; CI: 1.57-5.34), depressive symptoms (OR: 3.27; CI: 1.73-6.18) and anxiety at baseline (OR: 8.38; CI: 4.65-15.12) were independent predictors of anxiety 12 months post-PCI, adjusting for baseline demographic and clinical characteristics.
A limitation of the study is the attrition rate of 105 patients who did not complete the HADS at 12 months. No information was available on the use of psychotropic medication and participation in cardiac rehabilitation, which could serve as confounders.
Type-D exerted a stable effect on anxiety over time and was an independent predictor of anxiety 12 months post-PCI together with depressive symptoms and anxiety at baseline. The DS14 could be used as a screening tool in clinical practice to identify high-risk patients post-PCI.
我们研究了D型人格是否会随着时间的推移对焦虑产生稳定影响,以及D型人格作为经皮冠状动脉介入治疗(PCI)后12个月焦虑预测指标的临床相关性。
连续接受PCI治疗的稳定型或不稳定型心绞痛患者(n = 416)在基线时完成D型量表(DS14),并在基线和12个月时完成医院焦虑抑郁量表(HADS)。
基线时,26%的患者存在焦虑,其中67%的患者在PCI后12个月仍存在焦虑(p<0.001)。基线和12个月之间焦虑无显著变化(p = 0.96),D型人格与时间的交互作用也不显著(p = 0.41)。然而,D型患者的焦虑水平显著高于非D型患者(p<0.001)。在调整基线人口统计学和临床特征后,D型人格(OR:2.89;CI:1.57 - 5.34)、抑郁症状(OR:3.27;CI:1.73 - 6.18)和基线时的焦虑(OR:8.38;CI:4.65 - 15.12)是PCI后12个月焦虑的独立预测因素。
该研究的一个局限性是有105名患者在12个月时未完成HADS,存在失访率。关于精神药物的使用和心脏康复参与情况没有可用信息,这些可能是混杂因素。
D型人格随着时间的推移对焦虑产生稳定影响,并且与抑郁症状和基线时的焦虑一起是PCI后12个月焦虑的独立预测因素。DS14可作为临床实践中的筛查工具,以识别PCI后的高危患者。