Al-Qezweny M N A, Utens E M W J, Dulfer K, Hazemeijer B A F, van Geuns R-J, Daemen J, van Domburg R
Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands.
Neth Heart J. 2016 Sep;24(9):538-43. doi: 10.1007/s12471-016-0860-4.
There are indications that type D personality and depression are associated in patients treated with percutaneous coronary intervention (PCI). However, at present it is unclear whether this relationship holds in the long term. This study's aim was to investigate the association between type D personality at 6 months post-PCI (baseline), and depression at 10-year follow-up. A secondary aim was to test the association between type D personality at baseline and anxiety at 10-year follow-up.
A cohort of surviving consecutive patients (N = 534) who underwent PCI between October 2001 and October 2002. Patients completed the type D personality scale (DS14) measuring type D personality at baseline, and the Hospital Anxiety and Depression Scale (HADS) measuring anxiety and depression at baseline and at 10 years post-PCI.
At baseline, the prevalence of type D personality was 25 % (135/534). Type D personality patients were more often depressed (42 %) than non-type D personality patients (9 %). Response rate of anxiety and depression questionnaires at 10 years was 75 %. At 10-year follow-up, 31 % of type D personality patients were depressed versus 13 % of non-type D personality patients. After adjustments, baseline type D personality remained independently associated with depression at 10 years (OR = 3.69; 95 % CI [1.89-7.19]). Type D showed a similar association with anxiety at 10 years, albeit somewhat lower (OR = 2.72; 95 % CI [1.31-5.63]).
PCI patients with type D personality had a 3.69-fold increased risk for depression and a 2.72-fold increased risk for anxiety at 10 years of follow-up.
有迹象表明,接受经皮冠状动脉介入治疗(PCI)的患者中,D型人格与抑郁症有关联。然而,目前尚不清楚这种关系在长期内是否成立。本研究的目的是调查PCI术后6个月(基线)时的D型人格与10年随访时的抑郁症之间的关联。次要目的是检验基线时的D型人格与10年随访时的焦虑症之间的关联。
选取2001年10月至2002年10月期间连续接受PCI治疗的存活患者队列(N = 534)。患者在基线时完成测量D型人格的D型人格量表(DS14),并在基线时以及PCI术后10年完成测量焦虑和抑郁的医院焦虑抑郁量表(HADS)。
在基线时,D型人格的患病率为25%(135/534)。D型人格患者比非D型人格患者更易患抑郁症(42%对9%)。10年时焦虑和抑郁问卷的回复率为75%。在10年随访时,31%的D型人格患者患有抑郁症,而非D型人格患者为13%。经过调整后,基线时的D型人格在10年时仍与抑郁症独立相关(OR = 3.69;95%CI[1.89 - 7.19])。D型人格在10年时与焦虑症也有类似关联,尽管略低(OR = 2.72;95%CI[1.31 - 5.63])。
D型人格的PCI患者在10年随访时患抑郁症的风险增加3.69倍,患焦虑症的风险增加2.72倍。