Fujii Tsukasa, Ogino Satoshi, Arimoto Hiroe, Irifune Morihiro, Iwata Nobuko, Ookawachi Ichiro, Kikumori Hiroshi, Seo Ritsu, Takeda Mariko, Tamaki Akiko, Baba Kenji, Nose Michihiro
Graduate School of Allied Health Sciences, Faculty of Medicine, Osaka University.
Arerugi. 2007 Feb;56(2):109-17.
It is reported that the health-related quality of life (HRQL) is an important outcome in the Japanese Cedar Pollinosis (JCP) treatment. In Japan, the disease-specific Japan Rhino-conjunctivitis Quality of Life Questionnaire (JRQLQ) and the generic SF-36 Health Survey (SF-36) has been used. The aim of this study is to investigate more profitable QOL by using both the disease-specific questionnaire and the non-disease-specific questionnaire together.
411 patients with JCP who visited 10 ENT clinics in Osaka from March 14 to March 26 (peak pollen season) in 2005 were questioned, and 240 patients were engaged in this study as subjects. In this study, the QOL scores were evaluated using the JRQLQ and SF-8 Health Survey (Japanese Version), a new, even shorter generic health survey.
Using factor analysis and the correlation matrix, we showed that the disease-specific and the general health instrument covered a different half the total measurable HRQL. There was some correlation between the SF-8 items with the JRQLQ domains. There was little correlation between the SF-8 items and symptom scores, while, there was high correlation between the JRQLQ and symptom scores. The "Usual daily activities" domain in the JRQLQ correlated with any rhinoconjunctivitis symptoms.
Both JRQLQ and SF-8 can be used to assess the quality of life of patients with JCP. Each instrument measures the aspects of the HRQL that hardly overlaps. For an assessment of the HRQL in JCP that is complete and responsive both instruments should be employed together.
据报道，健康相关生活质量（HRQL）是日本雪松花粉症（JCP）治疗的一项重要结果。在日本，已经使用了针对该疾病的《日本鼻结膜炎生活质量问卷》（JRQLQ）和通用的《SF - 36健康调查》（SF - 36）。本研究的目的是通过同时使用针对疾病的问卷和非针对疾病的问卷来研究更具价值的生活质量。
对2005年3月14日至3月26日（花粉高峰期）期间前往大阪10家耳鼻喉科诊所就诊的411例JCP患者进行了询问，其中240例患者作为研究对象参与本研究。在本研究中，使用JRQLQ和《SF - 8健康调查》（日文版）对生活质量得分进行评估，后者是一种新的、更简短的通用健康调查。
通过因子分析和相关矩阵，我们发现针对疾病的和一般健康状况的测量工具涵盖了可测量的总HRQL的不同部分。SF - 8项目与JRQLQ领域之间存在一定相关性。SF - 8项目与症状得分之间相关性较小，而JRQLQ与症状得分之间相关性较高。JRQLQ中的“日常活动”领域与任何鼻结膜炎症状相关。
JRQLQ和SF - 8均可用于评估JCP患者的生活质量。每种工具测量的HRQL方面几乎没有重叠。为了对JCP患者的HRQL进行全面且灵敏的评估，两种工具应一起使用。
