Karnaukhova N A, Sergievich L A, Sorbuchev S I, Manokhina I A, Rodionov A V, Karnaukhov V N
Biofizika. 2007 Jan-Feb;52(1):141-6.
Changes in the functional activity of the synthesis apparatus of rat blood lymphocytes under different scheme in application of bioadditive Soma after acute X-irradiation by fluorescent microspectrometry. Some metabolic indices in animals were investigated too. It has been shown the bioadditive Soma using in norm reliably increased the synthetic activity on days 13 and 20. Preliminary Soma using during a month followed by the same interval increased the animal radioresistance (scheme 1), while the Soma using immediately after irradiation (scheme 2) revealed no pronounced radioprotective effect. It was found the Soma increased metabolism that may be important to recover homeostasis. The results show the expediency of further investigation of the Soma radioprotective properties with different concentrations and schemes as well as the necessity of monitoring the immune system during Soma using.
通过荧光显微光谱法研究急性X射线照射后，按照不同方案应用生物添加剂Soma时大鼠血液淋巴细胞合成装置的功能活性变化。同时也研究了动物的一些代谢指标。结果表明，正常情况下使用生物添加剂Soma能在第13天和第20天可靠地提高合成活性。在一个月内预先使用Soma，随后间隔相同时间，可提高动物的辐射抗性（方案1），而在照射后立即使用Soma（方案2）则未显示出明显的辐射防护作用。发现Soma可增强代谢，这可能对恢复体内平衡很重要。结果表明，有必要进一步研究不同浓度和方案下Soma的辐射防护特性，以及在使用Soma期间监测免疫系统的必要性。
