Wang Gen-Shu, Lu Min-Qiang, Yang Yang, Cai Chang-Jie, Zheng Feng-Ping, Wang Wei-Dong, Li Hua, Xu Chi, Yi Shu-Hong, Yi Hui-Min, Chen Gui-Hua
Organ Transplantation Institute, Sun Yat-Sen University, Liver Transplantation Center, Affiliated Third Hospital, Sun Yat-Sen University, Guangzhou, China.
Zhonghua Wai Ke Za Zhi. 2006 Nov 1;44(21):1453-5.
To investigate the practical value of endoscopic retrograde cholangiography (ERC) in biliary complications after liver transplantation.
The data of 71 biliary complications after liver transplantation were analyzed retrospectively. All patients were diagnosed and treated by ERC in our center from October 2003 to March 2006. The biliary complications included 52 cases of biliary stricture, 6 biliary leakage and 13 biliary stone.
The diagnostic rate of ERC for biliary stricture, leakage and stone was 98.1% (51/52), 100% (6/6) and 100% (13/13), respectively. The cure rate of interventional therapy through therapeutic ERC for anastomotic, extrahepatic, hilar, intrahepatic and diffuse biliary stricture was 66.7% (4/6), 66.7% (10/15), 0 (0/7), 0 (0/2) and 0 (0/21), respectively. And that for biliary leakage, common bile duct and intrahepatic bile duct stone was 66.7% (4/6), 77.8% (7/9) and 0 (0/4), respectively.
ERC is effective for diagnosis of biliary complications after liver transplantation. The effect of interventional therapy through ERC varies with the type of biliary complications. Only part of biliary complications (anastomotic stricture, extrahepatic biliary stricture, gently and moderate biliary leakage, common bile duct stone) can be cured by interventional therapy through ERC.
探讨内镜逆行胆管造影术(ERC)在肝移植术后胆道并发症中的应用价值。
回顾性分析71例肝移植术后胆道并发症患者的资料。2003年10月至2006年3月期间,所有患者均在本中心接受ERC诊断及治疗。胆道并发症包括52例胆管狭窄、6例胆漏和13例胆管结石。
ERC对胆管狭窄、胆漏和结石的诊断率分别为98.1%(51/52)、100%(6/6)和100%(13/13)。通过治疗性ERC进行介入治疗,吻合口、肝外、肝门、肝内及弥漫性胆管狭窄的治愈率分别为66.7%(4/6)、66.7%(10/15)、0(0/7)、0(0/2)和0(0/21)。胆漏、胆总管及肝内胆管结石的治愈率分别为66.7%(4/6)、77.8%(7/9)和0(0/4)。
ERC对肝移植术后胆道并发症的诊断有效。通过ERC进行介入治疗的效果因胆道并发症类型而异。只有部分胆道并发症(吻合口狭窄、肝外胆管狭窄、轻度及中度胆漏、胆总管结石)可通过ERC介入治疗治愈。