Fernández-Simon Alejandro, Díaz-Gonzalez Alvaro, Thuluvath Paul J, Cárdenas Andrés
GI/Endoscopy Unit, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, University of Barcelona, Villarroel 170, Esc 3-2, Barcelona 08036, Spain.
Medical Director, Institute for Digestive Health & Liver Disease, Mercy Medical Center, 301 Street, Paul Place, Baltimore, MD 21202, USA.
Clin Liver Dis. 2014 Nov;18(4):913-26. doi: 10.1016/j.cld.2014.07.009. Epub 2014 Aug 22.
Biliary complications after liver transplantation (LT) are an important cause of morbidity and mortality. In most cases, an anastomosis of the bile duct is performed as a duct-to-duct reconstruction, which makes endoscopic therapy with endoscopic retrograde cholangiography (ERC) feasible. Biliary anastomotic strictures (AS) are the most common cause of biliary complications. The early detection of an AS, which can sometimes be challenging given that its clinical presentation is often subtle, is of key importance to obtain high treatment success. In this review, we focus on the management of AS after LT with a special emphasis on ERC.
肝移植(LT)后的胆道并发症是发病和死亡的重要原因。在大多数情况下,胆管吻合采用端端重建,这使得通过内镜逆行胆管造影(ERC)进行内镜治疗成为可能。胆道吻合口狭窄(AS)是胆道并发症最常见的原因。AS的早期检测有时具有挑战性,因为其临床表现往往不明显,而早期检测对于获得高治疗成功率至关重要。在本综述中,我们重点关注肝移植后AS的管理,特别强调ERC。