[β2微球蛋白淀粉样变性表现为血液透析患者的肠穿孔]

[Beta 2-microglobulin amyloidosis presenting as intestinal perforation in a haemodialysis patient].

作者信息

Farah-Klibi F, Ferchichi L, Jarboui S, Ben Slama S, Zaouche A, Ben Jilani S, Zermani R

机构信息

Service d'anatomie et de cytologie pathologiques de l'hôpital Charles-Nicolle de Tunis, boulevard 9-Avril-1938, 1006 Tunis, Tunisie.

出版信息

Rev Med Interne. 2007 Apr;28(4):269-71. doi: 10.1016/j.revmed.2006.12.012. Epub 2007 Jan 9.

DOI:10.1016/j.revmed.2006.12.012

PMID:17349721

Abstract

Long term haemodialysis patient is subject to several complications such as generalised amyloidosis which is the result of deposits of beta2-microglobulin not depurated by haemodialysis. Digestive location causes ischemic accidents such as ulcer, infarctus, digestive haemorrhage, pseudo-obstruction and perforation manifested by a surgical emergency. Our observation is the 6th case of intestinal perforation caused by amyloidosis deposit reported in the literature.

摘要

长期血液透析患者易出现多种并发症，如全身性淀粉样变性，这是由于血液透析未能清除的β2-微球蛋白沉积所致。消化系统受累会引发缺血性意外，如溃疡、梗死、消化道出血、假性肠梗阻和穿孔，表现为外科急症。我们的观察病例是文献报道的第6例由淀粉样变性沉积导致的肠穿孔。