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Is there evidence for convergent evolution around human microsatellites?

作者信息

Webster Matthew T, Hagberg Jonas

出版信息

Mol Biol Evol. 2007 May;24(5):1097-100. doi: 10.1093/molbev/msm051. Epub 2007 Mar 8.

Abstract

A study by Vowles and Amos (2004) identified atypical patterns of base composition around human microsatellites and argued that microsatellites generate mutational biases in their flanking regions. Here, we perform simulations of molecular evolution using a simple model that suggest similar patterns can be produced without any such biases in genome evolution.

摘要

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