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耳鼻喉科实践中鼻喷雾剂的污染风险。

Risk of contamination of nasal sprays in otolaryngologic practice.

作者信息

Aydin Erdinc, Hizal Evren, Akkuzu Babur, Azap Ozlem

机构信息

Department of Otorhinolaryngology, Baskent University Faculty of Medicine, Ankara, Turkey.

出版信息

BMC Ear Nose Throat Disord. 2007 Mar 13;7:2. doi: 10.1186/1472-6815-7-2.

DOI:10.1186/1472-6815-7-2
PMID:17352835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1828065/
Abstract

BACKGROUND

Reusable nasal-spray devices are frequently used in otolaryngologic examinations, and there is an increasing concern about the risk of cross-contamination from these devices. The aim of our study was to determine, by means of microbiologic analysis, the safety of a positive-displacement or pump-type atomizer after multiple uses.

METHODS

A reusable nasal spray bottle, pump, and tips were used in the nasal physical examination of 282 patients admitted to a tertiary otolaryngology clinic. The effectiveness of 2 different methods of prophylaxis against microbiologic contamination (the use of protective punched caps or rinsing the bottle tip with alcohol) was compared with that of a control procedure.

RESULTS

Although there was no statistically significant difference in positive culture rates among the types of nasal spray bottles tested, methicillin-resistant coagulase-negative staphylococci were isolated in 4 of 198 cultures.

CONCLUSION

Given these findings, we concluded that additional precautions (such as the use of an autoclave between sprays, disposable tips, or disposable devices) are warranted to avoid interpatient cross-contamination from a reusable nasal spray device.

摘要

背景

可重复使用的鼻喷雾装置常用于耳鼻喉科检查,人们越来越关注这些装置造成交叉污染的风险。我们研究的目的是通过微生物分析确定正位移或泵式雾化器多次使用后的安全性。

方法

在一家三级耳鼻喉科诊所对282例住院患者进行鼻体格检查时,使用了一个可重复使用的鼻喷雾瓶、泵和喷头。将两种不同的预防微生物污染方法(使用带孔保护帽或用酒精冲洗瓶头)的有效性与对照程序进行了比较。

结果

尽管在测试的鼻喷雾瓶类型中,阳性培养率没有统计学上的显著差异,但在198份培养物中有4份分离出耐甲氧西林凝固酶阴性葡萄球菌。

结论

基于这些发现,我们得出结论,有必要采取额外的预防措施(如喷雾之间使用高压灭菌器、一次性喷头或一次性装置),以避免可重复使用的鼻喷雾装置在患者之间造成交叉污染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5cc/1828065/f2a373941e39/1472-6815-7-2-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5cc/1828065/1dfb8a74c641/1472-6815-7-2-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5cc/1828065/f2a373941e39/1472-6815-7-2-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5cc/1828065/1dfb8a74c641/1472-6815-7-2-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5cc/1828065/f2a373941e39/1472-6815-7-2-2.jpg

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本文引用的文献

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ORL Head Neck Nurs. 2005 Spring;23(2):25-7.
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An assessment for the presence of bacterial contamination of Venturi principle atomizers in a clinical setting.
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阻塞性睡眠呼吸暂停中使用的正压通气设备的污染程度。
Clin Exp Otorhinolaryngol. 2024 May;17(2):160-167. doi: 10.21053/ceo.2024.00025. Epub 2024 Mar 19.
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Association of CPAP bacterial colonization with chronic rhinosinusitis.持续气道正压通气细菌定植与慢性鼻-鼻窦炎的关系。
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Bacterial contamination of multiple-use atomizers commonly used in Japan.日本常用的多用途雾化器的细菌污染情况。
Indian J Otolaryngol Head Neck Surg. 2009 Sep;61(3):193-6. doi: 10.1007/s12070-009-0064-y. Epub 2009 Sep 27.
Multi-use Venturi nasal atomizer contamination in a clinical rhinologic practice.
临床鼻科实践中多用途文丘里鼻腔雾化器的污染情况
Am J Rhinol. 2004 May-Jun;18(3):151-6.
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Venturi atomizers as potential sources of patient cross-infection.文丘里雾化器作为患者交叉感染的潜在来源。
Am J Infect Control. 2003 Nov;31(7):441-4. doi: 10.1067/mic.2003.74.
6
Multiple-use atomizers in outpatient otolaryngology clinics are not necessarily an infectious risk.门诊耳鼻喉科诊所中多次使用的雾化器不一定存在感染风险。
Otolaryngol Head Neck Surg. 2003 Apr;128(4):447-51. doi: 10.1016/S0194-59980300125-6.
7
The comparative risks of bacterial contamination between a venturi atomizer and a positive displacement atomizer.文丘里雾化器与正位移雾化器之间细菌污染的比较风险。
Am J Rhinol. 2002 Jul-Aug;16(4):181-6; discussion 186.
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Cluster of tuberculosis cases in North Carolina: possible association with atomizer reuse.
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9
The need for and development of a single use disposable nasal spray.一次性使用鼻喷雾剂的需求及开发
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10
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J Hosp Infect. 1994 Dec;28(4):315-21. doi: 10.1016/0195-6701(94)90095-7.