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持续气道正压通气细菌定植与慢性鼻-鼻窦炎的关系。

Association of CPAP bacterial colonization with chronic rhinosinusitis.

机构信息

Department of Otolaryngology - Head & Neck Surgery, Western University, London, Ontario.

出版信息

J Clin Sleep Med. 2013 Aug 15;9(8):747-50. doi: 10.5664/jcsm.2910.

Abstract

STUDY OBJECTIVE

The purpose of our study was to investigate whether bacterial colonization of the continuous positive air-way pressure (CPAP) machine reservoirs occurred, and if so, if it was related to the development of chronic rhinosinusitis (CRS).

DESIGN

Prospective cohort study.

SETTING

London Health Sciences Center (LHSC).

PATIENTS

Regular CPAP users with obstructive sleep apnea (OSA).

INTERVENTIONS

N/A.

MEASUREMENTS AND RESULTS

Patient demographics were recorded and they were asked to fill out the chronic sinusitis survey (CSS) form. Patients then had their CPAP machines swabbed. An ANOVA was used to determine if the presence of microbacterial colonization was related to CSS scores. In total, 72 patients were included in the study. There was no significant difference in any of the scores between the group with positive cultures and the group without positive cultures.

CONCLUSIONS

Having a positive culture in the cpap reservoir does not seem to lead to an increased symptomatology of crs: although the reservoirs often become colonized, there seems to be no clinical impact.

摘要

研究目的

本研究旨在探讨持续气道正压通气(CPAP)机储水罐是否存在细菌定植,如果存在,是否与慢性鼻-鼻窦炎(CRS)的发生有关。

设计

前瞻性队列研究。

地点

伦敦健康科学中心(LHSC)。

患者

阻塞性睡眠呼吸暂停(OSA)的常规 CPAP 用户。

干预措施

无。

测量和结果

记录患者的人口统计学数据,并要求他们填写慢性鼻窦炎调查(CSS)表格。然后对患者的 CPAP 机器进行拭子采样。采用方差分析(ANOVA)来确定微生物定植的存在是否与 CSS 评分相关。共有 72 名患者纳入研究。在阳性培养组和阴性培养组之间,任何评分均无显著差异。

结论

CPAP 储水罐中存在阳性培养物似乎不会导致 CRS 症状加重:尽管储水罐经常被定植,但似乎没有临床影响。

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