Buhr Gwendolen T, White Heidi K
Department of Medicine, Division of Geriatrics, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA.
J Am Med Dir Assoc. 2007 Mar;8(3 Suppl 2):e101-13. doi: 10.1016/j.jamda.2006.12.012.
Difficult behaviors are relatively common challenges that can occur throughout the natural progression of dementia, but are particularly common in the mid to late stages of disease. These behaviors can be challenging to manage in nursing and assisted care facilities, and can cause distress to the caregivers and to the patients themselves. Our ability to manage these symptoms can have a profound effect on the patient's quality of life. This article reviews the appropriate assessment of behavioral and psychological symptoms of dementia (BPSD) and the literature supporting various nonpharmacologic and pharmacologic treatments. Nonpharmacologic approaches should be the initial focus for treatment of most BPSD, but should these prove inadequate, a variety of medications are available with varying degrees of clinical research to support their use in ameliorating BPSD.
困难行为是痴呆症自然发展过程中相对常见的挑战,但在疾病的中晚期尤为常见。在护理和辅助护理机构中,管理这些行为具有挑战性,并且会给护理人员和患者本人带来困扰。我们管理这些症状的能力会对患者的生活质量产生深远影响。本文回顾了对痴呆症行为和心理症状(BPSD)的适当评估以及支持各种非药物和药物治疗的文献。非药物方法应作为大多数BPSD治疗的初始重点,但如果这些方法被证明不足,有多种药物可供使用,并有不同程度的临床研究支持它们用于改善BPSD。