Gerlach Lauren B, Kales Helen C
Program for Positive Aging, Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109, USA.
Program for Positive Aging, Department of Psychiatry, University of Michigan, 4250 Plymouth Road, Ann Arbor, MI 48109, USA; Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI 48105, USA.
Psychiatr Clin North Am. 2018 Mar;41(1):127-139. doi: 10.1016/j.psc.2017.10.010. Epub 2017 Dec 7.
Behavioral and psychological symptoms of dementia (BPSD) are universally experienced by people with dementia throughout the course of the illness and cause a significant negative impact on quality of life for patients and caregivers. Nonpharmacologic treatments have been recommended as first-line treatment of BPSD by multiple professional organizations and should target patients with dementia factors, caregiver factors, and environmental factors. Psychotropic medications are often prescribed off-label without significant evidence to support their use. The Describe, Investigate, Create, Evaluate approach can provide a structured method to investigate and treat BPSD with flexibility to use in multiple treatment settings.
痴呆的行为和心理症状(BPSD)在痴呆患者的整个病程中普遍存在,对患者及其照护者的生活质量产生重大负面影响。多个专业组织已推荐非药物治疗作为BPSD的一线治疗方法,且应针对痴呆因素、照护者因素和环境因素的患者。精神药物的处方往往缺乏充分证据支持,属于超说明书用药。描述、调查、制定、评估方法可以提供一种结构化的方法来调查和治疗BPSD,并能灵活应用于多种治疗场景。