神经放射科医生的神经病理学：荧光原位杂交
Neuropathology for the neuroradiologist: fluorescence in situ hybridization.
作者信息
Wippold F J, Perry A
机构信息
Neuroradiology Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA.
出版信息
AJNR Am J Neuroradiol. 2007 Mar;28(3):406-10.
Abstract
Fluorescence in situ hybridization is a molecular cytogenetic technique that localizes segments of DNA within tumor cells by using dyes that are visible with a fluorescent microscope. The technique has proved useful in typing a variety of tumors such as oligodendrogliomas and in understanding the genetic forces driving oncogenesis.
摘要
荧光原位杂交是一种分子细胞遗传学技术，它通过使用在荧光显微镜下可见的染料来定位肿瘤细胞内的DNA片段。该技术已被证明在对多种肿瘤（如少突胶质细胞瘤）进行分型以及理解驱动肿瘤发生的遗传因素方面很有用。
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