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面神经麻痹的眼科治疗:综述

Ophthalmic management of facial nerve palsy: a review.

作者信息

Rahman Imran, Sadiq S Ahmed

机构信息

Manchester Royal Eye Hospital, Manchester, United Kingdom.

出版信息

Surv Ophthalmol. 2007 Mar-Apr;52(2):121-44. doi: 10.1016/j.survophthal.2006.12.009.

Abstract

Facial nerve palsy affects individuals of all ages, races, and sexes. Psychological and functional implications of the paralysis present a devastating management problem to those afflicted, as well as the carriers. Since Sir Charles Bell's original description of facial palsy in 1821, our understanding and treatment options have expanded. It is essential that a multidisciplinary approach, encompassing ophthalmologists; Ear, Nose, and Throat surgeons; plastic surgeons; and psychologists work closely to optimize patient management in a staged approach. Although the etiology remains unknown, strong histological, cerebral spinal fluid, and radiological evidence suggests a possible association with herpes simplex virus in idiopathic facial nerve palsy (Bell's palsy). The use of steroids has been suggested as a means of limiting facial nerve damage in the acute phase. Unfortunately, no single randomized control trial has achieved an unquestionable benefit with the use of oral steroid therapy and thus remains controversial. In the acute phase, ophthalmologists play a pivotal role in preventing irreversible blindness from corneal exposure. This may be successfully achieved by using intensive lubrication, medical therapy (botulinum toxin), or surgery (upper lid weighting or tarsorraphy). Once the cornea is adequately protected and recovery deemed unlikely, longer term planning for eyelid and facial reanimation may take place in an individualized manner. Onset is sudden and management potentially lengthy. Physician empathy, knowledge, and experience are essential in averting long-term lifestyle and psychological discomfort for patients.

摘要

面神经麻痹影响所有年龄、种族和性别的人群。这种麻痹带来的心理和功能影响给患者及其家属带来了极具破坏性的管理难题。自1821年查尔斯·贝尔爵士首次描述面神经麻痹以来,我们对其的理解和治疗选择都有所扩展。至关重要的是,多学科方法,包括眼科医生、耳鼻喉科外科医生、整形外科医生和心理学家,要紧密合作,以分阶段的方式优化患者管理。虽然病因仍然不明,但强有力的组织学、脑脊液和放射学证据表明,特发性面神经麻痹(贝尔麻痹)可能与单纯疱疹病毒有关。有人建议使用类固醇作为在急性期限制面神经损伤的一种方法。不幸的是,没有一项单一的随机对照试验通过使用口服类固醇疗法取得无可争议的益处,因此仍然存在争议。在急性期,眼科医生在预防角膜暴露导致的不可逆失明方面发挥着关键作用。这可以通过强化润滑、药物治疗(肉毒杆菌毒素)或手术(上睑加重或睑缘缝合术)成功实现。一旦角膜得到充分保护且恢复无望,就可以以个体化的方式进行眼睑和面部重建的长期规划。发病突然,治疗可能需要很长时间。医生的同理心、知识和经验对于避免患者长期的生活方式和心理不适至关重要。

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