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采用850纳米扫频激光的高速、高分辨率光学相干断层扫描视网膜成像。

High-speed, high-resolution optical coherence tomography retinal imaging with a frequency-swept laser at 850 nm.

作者信息

Srinivasan V J, Huber R, Gorczynska I, Fujimoto J G, Jiang J Y, Reisen P, Cable A E

机构信息

Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

出版信息

Opt Lett. 2007 Feb 15;32(4):361-3. doi: 10.1364/ol.32.000361.

DOI:10.1364/ol.32.000361
PMID:17356653
Abstract

High-speed, high-resolution optical coherence tomography (OCT) imaging of the human retina is demonstrated using a frequency-swept laser at 850 nm. A compact external cavity semiconductor laser design, optimized for swept-source ophthalmic OCT, is described. The laser enables an effective 16 kHz sweep rate with >10 mm coherence length and a tuning range of approximately 35 nm full width at half-maximum, yielding an axial resolution of <7 micro m in tissue.

摘要

利用一台850nm的扫频激光器展示了对人眼视网膜的高速、高分辨率光学相干断层扫描(OCT)成像。描述了一种针对扫频源眼科OCT进行优化的紧凑型外腔半导体激光器设计。该激光器能够实现16kHz的有效扫频速率,相干长度大于10mm,半高全宽调谐范围约为35nm,在组织中产生的轴向分辨率小于7μm。

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