Zohav Efraim, Orvieto Raoul, Anteby Eyal Y, Segal Octav, Meltcer Simion, Tur-Kaspa Ilan
Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel.
J Assist Reprod Genet. 2007 Jun;24(6):259-61. doi: 10.1007/s10815-007-9121-1. Epub 2007 Mar 14.
To evaluate the role of 3-D US measurement of the endometrium during early IVF-pregnancy and before the appearance of gestational sac in the prediction of pregnancies outcome.
60 pregnant women following IVF treatment were included in the study. The women underwent transvaginal 3D US measurements of endometrial volume and thickness on day 15-17 post ET. Patients were followed and classified according to pregnancy outcome into 2 further groups. The group with early pregnancy loss and the group with ongoing pregnancy.
While no differences were observed between those who miscarried and those who did not in gestational age, endometrial thickness or volume, spontaneous early pregnancy loss was significantly higher in patients with endometrial volume <2 mL as compared to those with endometrial volume >2 mL.
3-D US measurement of endometrial volume of less than 2 mL during early IVF pregnancy and prior to the appearance of gestational sac is a powerful predictor of pregnancy loss.
评估在体外受精-妊娠早期且妊娠囊出现之前，三维超声测量子宫内膜对妊娠结局的预测作用。
本研究纳入60例接受体外受精治疗后的孕妇。这些女性在胚胎移植后第15 - 17天接受经阴道三维超声测量子宫内膜体积和厚度。根据妊娠结局将患者进一步分为两组：早期妊娠丢失组和持续妊娠组。
虽然流产者与未流产者在孕周、子宫内膜厚度或体积方面未观察到差异，但与子宫内膜体积>2 mL的患者相比，子宫内膜体积<2 mL的患者自然早期妊娠丢失率显著更高。
在体外受精妊娠早期且妊娠囊出现之前，三维超声测量子宫内膜体积小于2 mL是妊娠丢失的有力预测指标。
