Petersen Eric, Li Bingquan, Fang Xiaohua, Luo Haobin, Samuilov Vladimir, Gersappe Dilip, Sokolov Jonathan, Chu Benjamin, Rafailovich Miriam
Harvard University, Cambridge, MA 02138, USA.
Phys Rev Lett. 2007 Feb 23;98(8):088102. doi: 10.1103/PhysRevLett.98.088102. Epub 2007 Feb 20.
We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.